Prasad, S
Cardile A., Passarini C., Zanr V., Fiore A., Menegazzi M., Antioxidants (Basel) 2023, 12
First of all, intracellular iron generally exists in the form of Fe 2+ , which can produce OH through the Fenton reaction, and then react with polyunsaturated fatty acids in the plasma membrane to produce ROS, resulting in iron-regulated death
Combining traditional forms of treatment, mainly pharmacotherapy for conditions, with normalization of the intestinal barrier and the state of microbiota can greatly enhance the efficacy and effectiveness of many therapies
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